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A liquid pharmaceutical composition consisting essentially of a) 3.2 mg/ml semaglutide, optionally b) no more than 0.1 %(w/w) phenol, c) above 6.4 mg/ml sodium chloride, d) buffer, e) at least 60% water, optionally f) histidine, optionally g) one or more agents for adjusting pH, such as HCI, NaOH, or acetate, and said composition optionally has a pH of 6-10 such as 7-8

Penn Metabolic Medicine, Department of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA | Journal: The American Journal of Clinical Nutrition , Volume 124 (2026), Article 101403 | DOI: | Clinical Trial Registration: ClinicalTrials.gov, NCT05548647

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Wawrzyniak & Balawender 2022)