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doi: 10.3389/FPHAR.2023.1147414 263 Amir AslaniBGhobadiS

At week 20, the change from baseline in HbA1c in patients treated with JANUVIA (N=95) was 0.06% compared to 0.23% in patients treated with placebo (N=95), a difference of -0.17% (95% CI: -0.62, 0.28)

These doses were necessary to achieve measurable CNS effects in rodents, but sublingual or subcutaneous routes allow effective dosing at 15mg in research contexts

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