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The modern form emerged with the 2003 patent by Hon Lik for a nicotine delivery system that vaporized liquid to deliver nicotine to the user in an aerosol, leading to sales of the first e-cigarette in 2004 in China [46]

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In the long run, however, the huge health costs of treating hundreds of millions of smokers are sure to catch up with China and other countries, and they will probably follow the West's lead in trying to discourage smoking

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