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This protective action can help maintain your skin's natural radiance and prevent further pigmentation issues

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For example, a recent study examined animals that had a significant mutation in the growth hormone releasing hormone receptors (GHRHR) which led to decreased levels of circulating GH

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Taken together, the researchers concluded that thyroid function may affect mast cells, and that mast cell degranulation could affect thyroid function.[ref] In patients with autoimmune thyroid disease, mast cells infiltrate the thyroid gland and then degranulate.[ref] Animal studies show that hypothyroidism (low thyroid hormone levels) increases the number of mast cells by up to 4.5-fold