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During the second quarter of 2025, tobacco prices in Spain reached 5693 USD/MT in June

Despite the tobacco industry claims, a growing body of evidence from independent studies warns about the health effects of novel nicotine-containing products 2 , particularly when combined with conventional cigarette (CC) smoking (dual use) 8-10

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Nicotine exert potential oncogenic effects primarily through nicotinic acetylcholine receptors, without involving signal pathways or other receptors