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Acknowledgments We acknowledge Indonesian Cosmetic Dermatology Study Group, who supported the study

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Reference-standard literature describes the use of RP-HPLC to evaluate lot homogeneity, stability, identity, content, and purity for synthetic peptide standards [18]

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Germ free (GF) mice have a different mucus layer than conventionally raised mice: in GF mice, the number of filled goblet cells is lower, and the small intestinal mucus is strictly anchored to the goblet cells and cannot be aspirated off