While earlier trials did not have dedicated RCTs at their disposal, studies such as the SOUL trial had 3 prior RCTs to refer to, as far as baseline CV risk estimation was concerned
semaglutide for heart health Heart disease is the leading cause of death for people with diabetes, making cardiovascular protection a key factor
For non-diabetics taking GLP agonists for other reasons most likely reducing body weight the results of this study may not be applicable as the interaction of diabetes-related inflammation, and such may be the reason for such wide-ranging GLP agonist effects. The study authors conclude that their results provide insights into the benefits and risks of GLP-1R and may be useful for informing clinical care and guiding research agendas
137 A randomized, placebo-controlled, crossover trial involving 30 subjects with mild sleep complaints found 14 days of treatment with 7.5 mg crocetin, a compound extracted from saffron, increased the intensity of sleep drive as measured with EEG
In fact, some of the strongest evidence for the benefits of glutathione in reproduction relates to sperm health
