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It plays a key role in cell migration, blood vessel formation, and tissue regeneration, making it a valuable compound for recovery-focused research

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But topical absorption remains variable and may require higher concentrations for systemic effects

The major cardiovascular safety trials The SUSTAIN-6 trial enrolled 3,297 patients with type 2 diabetes and high cardiovascular risk, following them for two years on semaglutide 0.5 mg or 1.0 mg weekly versus placebo

Thirty-seven (49%) patients used liraglutide, 45 (60%) used semaglutide, 13 (17%) used exenatide, 6 (8%) used dulaglutide, and 8 (11%) used tirzepatide