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Accumulation of Pael-R causing ER stress could be relevant to the pathological mechanisms that underlie autosomal recessive PD

Pantothenic acid (vitamin B5) has been shown to increase glutathione synthesis by improving cellular energetics [53]

2 The human genome normally contains two sex chromosomes that determine the sex of an individual: two X chromosomes in women and one X and one Y sex chromosome in men

FIGURE 3 PEROXIREDOXINTHIOREDOXIN REDOX CYCLE Peroxiredoxins constitute a family of thiol-specific peroxidases that rely on thioredoxins (Trxs) as the hydrogen donor for the reduction of H 2 O 2 and lipid hydroperoxides ( 2 O 2 produced by the mitochondrial respiratory chain

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