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Researcher Steve Lee, an associate professor of psychology at UCLA and lead author of the 2013 meta-analysis agrees: "I have little doubt that stimulant medication is being prescribed without careful diagnostic procedures and that's a significant problem." "But it's also the case that in some communities children, and probably some adults, who could respond therapeutically and safely are being underprescribed and not getting the treatment they need," he says.

Since that time, heliox mixtures delivered in close fitting delivery devices have been used in the management of asthma exacerbations to decrease the work of breathing and enhance the delivery of oxygen to the gas exchange zone by aiding in laminar airflow throughout the tracheobronchial tree