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I was a cross between his bass player and his little brother

According to Greens Dictionary of Slang, the noun was originally used to describe any unpleasant experience, depressing circumstances. (The phrase riding a bummer, which popped up in Tom Wolfes 1968 book The Electric Kool-Aid Acid Test, referred to a bad trip on a motorcycle.) It soon spread to describe a bad drug trip, whether you were part of a biker crew or not

doi:10.1136/tobaccocontrol-2016-053030

In 2009, an estimated 46.6 million, or 20.6% of adults (aged 18+) were current smokers

Smoking Affects Arthritis Treatment Methotrexate, the mainstay drug for RA, is effective for only about half of the people who use it