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Endogenous extra-cellular heat shock protein 72: releasing signal(s) and function

Some peptides occur naturally, regulating everyday functions like appetite, digestion, and metabolism, while others are synthesized to mimic or amplify those same natural signals

Several repurposed diabetes drugs and natural compounds have been shown to exert neuroprotective effects by inhibiting ferroptosis

Although the specific compounds in cinnamon chiefly responsible for its glucose-lowering and insulin-sensitizing effects remain under investigation, cinnamaldehyde is of particular interest, as are polyphenols and other compounds including proanthocyanidins, flavones, catechins, coumarin, eugenol, beta-caryophyllene, and trans-cinnamic acid

Once in the mitochondrion, they become substrates of -oxidation and produce a number of adenosine triphosphate molecules that are proportional to the length of the number of carbons in their chain