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During the resolution of inflammation, SPMs produced by polymorphonuclear cells and macrophages act to limit local tissue damage caused by inflammatory responses, including signaling cessation of polymorphonuclear cell infiltration, macrophage switching to an anti-inflammatory phenotype, apoptotic cell clearance, and reducing pain caused by nociceptor sensitization (49, 61)

doi: 10.1111/j.1365-2249.2006.03295.x 89 HeoYJJooYBOhHJParkMKHeoYMChoMLet al

When paired with ceramide, it helps reduce transepidermal water loss and boost hydration. And the triple-lipid complex mirrors skins natural lipids to leave it feeling supple