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The main limitation is that the travel, cash handling, and purchasing protocol required the study to be within a single county

Addiction develops as a result of this

The principle of operation is based on heating a nicotine solution in propylene glycol and/or glycerine (e-liquid), turning it into aerosol (commonly called vapour), which is then inhaled by the user

I have never been a smoker but I have also seen first-hand the devastating impact it can have from watching my grandmother struggle to overcome her addiction before it eventually killed her, following a short battle with lung cancer, at 68

"We must do more to stem what I see as an epidemic of use of e-cigs among teens, and deeply disturbing trends that show no sign of abating," FDA Commissioner Scott Gottlieb said