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Meltzer H, Gill B, Hinds K, Petticrew M

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Of note, in our population most of this effect was driven by an increase in the late diastolic component of mitral annulus motion (Figure 5, top panels), with only a nonsignificant trend towards a reduction in the early diastolic component

Food and Drug Administration says

8 Primes the brain for other substance use, as shown in longitudinal studies linking adolescent vaping to subsequent smoking and cannabis use