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1 missed cleavage was allowed, and the following variable modifications were searched: Methionine oxidation (up to 3), N-terminal acetylation (1), carbamidomethylation (up to 2) and modification by the molecule (1)

Secondly Retatrutide is not marketed in pharmaceuticals: it exists in Phase 3 at Eli Lilly, without marketing authorization or European or American market access

This study indicates the involvement of epigenetic modifications such as small, non-coding RNAs and microRNAs, which contributes to post-transcriptional regulation

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