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This was quantified using the following calculation (equation 3): Where CB = biota concentration and CM = medium (leachate or sediment) concentration

The toxic substances in cigarette smoke cause significant inflammation and excessive mucus production in the lungs, which, combined with the destruction of cilia, severely impair respiratory function

[15] In the 1950s, with studies suggesting that smoking may be linked with lung cancer, Lorillard introduced Halloween-themed adverts that tried to downplay the effects smoking has on one's health