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GH hypersecretion in severe hepatic failure can worsen insulin resistance, increase lipolysis, and exacerbate hepatic encephalopathy through altered amino acid metabolism

Of course, this is true, but there is more to this that worsens the situation significantly in untreated acromegaly

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Sleep and circadian research: Investigation of Sermorelins impact on sleep architecture and nocturnal GH release, aligning dosing with endogenous GH secretion cycles