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Chewing tobacco and snuff effects on your health The American Lung Association lists five potential long-term effects of chewing tobacco: Cancer of the mouth, esophagus, pancreas Gum disease Tooth decay Tooth loss White (or gray) patches in the mouth (leukoplakia) The long-term effects of chewing tobacco and snuff are detailed below

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When smoke or other substances consistently irritate the airway, goblet cell and mucus levels increase

Together, these findings indicate that smoking even a small number of cigarettes per day has substantial negative health effects and provide further evidence that smoking cessation benefits all smokers, regardless of how few cigarettes they smoke. About the National Cancer Institute (NCI): NCI leads the National Cancer Program and the NIHs efforts to dramatically reduce the prevalence of cancer and improve the lives of cancer patients and their families, through research into prevention and cancer biology, the development of new interventions, and the training and mentoring of new researchers

21, 29 The oral use of smokeless tobacco is estimated to be the greatest external source of human exposure to nitrosamines which are causative factors in tobacco-related human cancers