The clinical evidence for topical GHK-Cu is anchored by Pickart's landmark studies
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Growth hormone plays a key role in: Tissue repair Muscle maintenance Fat metabolism Sleep quality Healthy aging As we age, GH production naturally declines, contributing to slower recovery, reduced lean muscle, and increased body fat
Beyond the established roles of glucotoxicity and hemodynamic stress, accumulating evidence highlights the central role of profound metabolic disturbances in driving DKD pathogenesis [3,4,5,6,7,8]
Peer review Peer review information Nature Communications thanks Tara Sutherland and the other anonymous reviewer(s) for their contribution to the peer review of this work