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Increased IRP2 expression in COPD causes mitochondrial dysfunction due to iron overload, leading to increased airway epithelial cell death, inflammation and impaired mucociliary clearance (192, 193)

Khouja J N, Taylor A E, Munaf M R

A study released in the US in 2024, for example, found that vapes without nicotine decreased venous oxygen saturation in other words, caused the vapers lungs to take in less oxygen: Following either vaping or smoking, the researchers saw a significant decrease in resting blood flow velocity in the femoral artery, which runs along the thigh and supplies oxygenated blood to the entire lower body, CNN Health reports