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"Nicotine poisoning occurs when nicotine begins to exhibit more dire toxic effects on an individual." The Centers for Disease Control and Prevention (CDC) warns that 50 to 60 milligrams of nicotine is a deadly dose for an adult who weighs about 150 pounds

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Low nicotine products may be insufficient to help adult smokers switch and may support initiation in young people and increase the severity of dependence among adult smokers without supporting full switching 34