PLP-dependent enzymes have been classified into five structural classes known as Fold Type I-V (5): Fold Type I - aspartate aminotransferase family Fold Type II - tryptophan synthase family Fold Type III - alanine racemase family Fold Type IV - D-amino acid aminotransferase family Fold Type V - glycogen phosphorylase family The many biochemical reactions catalyzed by PLP-dependent enzymes are involved in essential biological processes, such as hemoglobin and amino acid biosynthesis, as well as fatty acid metabolism
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Back to Journals Journal of Pain Research Volume 12 Acetyl-L-carnitine in painful peripheral neuropathy: a systematic review Authors Di Stefano G, Di Lionardo A, Galosi E , Truini A, Cruccu G Received 9 October 2018 Accepted for publication 28 January 2019 Published 26 April 2019 Volume 2019:12 Pages 13411351 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor E Alfonso Romero-Sandoval Giulia Di Stefano, Andrea Di Lionardo, Eleonora Galosi, Andrea Truini, Giorgio Cruccu Department of Human Neuroscience, Sapienza University, Rome, Italy Abstract: Acetyl-L-carnitine (ALC) has shown a neuroprotective effect in patients with peripheral neuropathies of different etiologies
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Consistent naming prevents duplicate targeting and keeps the canonical entity clear
