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As one of the US states with one of the highest smoking rates[4], the state of Indiana has implemented in collaboration with the organization Tobacco Prevention and Cessation Commission of the Indiana State Department of Health (TPC), a tobacco control program aimed at reducing the use of all tobacco products in Indiana as well as reducing exposure to tobacco smoke[5]

Drug administration into the respiratory tract allows for maximum drug absorption due to the lungs large surface area, rapid uptake of the drug by the alveoli, and a rich blood supply contributing to high bioavailability (Vazda et al

Nicotine & Tobacco Research , 16(2), 236-243