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Description

Metabolites 11 (2), 109

7 (20), e14255 (2019)

Complete and easy to understand instructions

Cys 2 ) or cystine-free/GSH-supplemented (750 M) medium for 48 h, and the relative abundance of indicated intracellular (e-g) and extracellular (f-g) metabolites was determined

We calculated polygenic scores from genome-wide association studies (GWAS) for 127 traits and diseases, and used these to discover molecular correlates of polygenic risk (e.g., genetic risk for inflammatory bowel disease was negatively correlated with plasma cystine)