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J Nutr Sci Vitaminol 57(3):246250 Trexler ET, Persky AM, Ryan ED, Schwartz TA, Stoner L, Smith-Ryan AE (2019a) Acute effects of citrulline supplementation on high-intensity strength and power performance: a systematic review and meta-analysis

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After reviewing 25 randomized controlled trials, we found that: 56% of nutrition interventions delivered in primary care were cost-effective 20% were moderately cost-effective The strongest economic outcomes were observed for telehealth and diabetes-focused interventions Behind these findings was an extensive process of harmonising health economic data across countries, calculating Incremental Net Benefit (INB), and performing meta-analysis and sensitivity analyses to produce robust, comparable evidence for decision-making

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In the joints, it acts as a shock absorber and lubricant, allowing for smooth, pain-free movement