the most important crop in the virginia colony was tobacco "Tobacco Saves Colony: How One Transformed Jamestown" Bright Leaf Legacy | Virginia

In fact, mutant populations are ubiquitous in plant RNA viruses and their presence is rarely considered significant until the mutant phenotype dominates 29

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Greater tobacco retailer density was independently associated with worse health outcomes, including lower life expectancy, age-adjusted mortality, and death from chronic lower respiratory disease