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Those who smoked more had higher incidence than those who smoked less, which aligns with previous MEC analyses [3]

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The study also found an association between increased estrogen concentration and taking fluoxetinewhich may affect other reproductive hormones including gonadotropin hormone-releasing hormone (controls the production of sex hormones), follicle-stimulating hormone (plays a role in sexual development and reproduction), and luteinizing hormone (controls the menstrual cycle in women)

The rainfall in Hainan Island and southern Yunnan from May to October accounts for 70-80% of the annual precipitation, with distinct wet and dry seasons, frequent rainy days, and around 150 rainy days in most areas

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