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Naturally increasing GLP-1 through diet and lifestyle typically results in modest weight loss, said Sarah Al Allawi, MD, assistant professor of Medicine at Macon & Joan Brock Virginia Health Sciences EVMS Medical Group at Old Dominion University

Esta etapa es posterior a los estudios de fase 2, en los que se definieron las dosis adecuadas y se evaluaron su eficacia inicial y perfil de seguridad en grupos ms pequeos de pacientes

Macro- and microvascular complications, especially proteinuria and renal insufficiency, are more common in these patients, due to the pre-existent mitochondrial dysfunction in different organs (101)

GLP-1 receptor agonists might be effective in both reducing cardiovascular disease, and hepatic health (112)

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