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Heres a list of potential causes: Smoking and vaping Sun exposure Drinking from a straw or bottle Repeated facial expressions Pouting/smiling Playing musical instruments (like the recorder or harmonica) Genetics Lifestyle factors Among these, smoking, including vaping, is one of the primary factors leading to vertical, fine lines and wrinkles appearing around the mouth

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Source: American Heart Association Diet & Lifestyle Recommendations The Fatal Mix: Smoking + Alcohol Combining both substances has a synergistic effectaggravating cardiovascular harm above the risk level for each on its own