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The relative ranking of the different treatment was estimated for each outcome using p-score [22]

1-3 The REIMAGINE clinical program evaluating CagriSema in adults with T2D follows previously published results from the REDEFINE clinical program, evaluating CagriSema in adults with overweight or obesity with and without T2D

These include improved DNA repair (through PARP, another NAD+-dependent enzyme), enhanced autophagy (cellular cleanup), reduced inflammation, and mitochondrial quality control

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