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In Japan, deregulation of experimental stem cell treatments may prove harmful to many, as David Cyranoski writes in Stem Cells 2 Go. And so-called vaccine hesitancythe resistance by small clusters of individuals to get their children vaccinatedis spurring new strategies to track and tackle the spread of deadly diseases, as Lynne Peeples describes in Rethinking Herd Immunity. As always, enjoy the issue!