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Glial innate immunity in neurodegenerative diseases Early studies established that cytosolic DNA can elicit innate immune responses and innate inflammation, inducing type I interferons (IFNs), yet the molecular mechanism underlying this sensing remained unresolved (Seth et al., 2006)

PubMed Central , Clinical Immunology (Orlando, Fla.) , vol

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Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsbll T, SUSTAIN-6 Investigators