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Marijuana was first introduced to America by the settlers at Jamestown in 1611, at the same time as tobacco

However, this design often prompted smokers to modify their behaviortaking deeper, more frequent puffs, covering the ventilation holes, or smoking more cigarettes to satisfy their nicotine cravings

PubMed and Scopus databases were searched in April 2024 using the search terms: (never-smokers OR never smokers OR never smok* OR nive OR healthy) AND (e-cig* OR e-cigarette OR ENDS OR electronic cigarette*) AND (respir* OR lung) AND (cohort or observational or follow-up OR randomized controlled trial OR RCT)

Nuclear medicine imaging procedures are noninvasive and, with the exception of intravenous injections, are usually painless medical tests that help physicians diagnose and evaluate medical conditions

These approaches aim to restore mitochondrial integrity and function, thereby improving cellular resilience and reducing inflammation