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Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists

During the Yugoslav Civil War, when imports of tobacco from Yugoslavia were halted due to UN economic sanctions, some Bosnian, Croatian, and Serbian soldiers reportedly tried smoking by burning grape leaves instead of cigarettes

Older adults and those with a history of ulcers or gastrointestinal bleeding may be more vulnerable to more serious gastrointestinal side effects

But disaster struck and major work was needed

These ventilation holes appear to have a favourable effect on the concentration of harmful substances as they thin the smoke