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Description

J., Bharatha, A., Montanera, W

In the nucleus, Nrf2 promotes glutathione synthesis and regeneration by binding to antioxidant response elements on DNA and subsequently activating the transcription of antioxidant enzymes

Glutathione is primarily concentrated in the liver and is crucial to the body's detoxification process

Reversal of this age-associated decline using the NAD + precursor nicotinamide mononucleotide (NMN) restored functional fertility, even when treatment was started at a post-reproductive age