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This study, a systematic review and meta-analysis of 39 randomized clinical trials with 10,761 participants, found no evidence of an increased risk of suicide or attempted suicide, suicidal ideation, depression or death with varenicline. The authors did acknowledge that the drug could cause insomnia and abnormal dreams, side effects that were already well recognized
The key is matching the purchase to your routine
minimum purchase age laws may have larger effects over a longer time period, or in places with weaker existing tobacco control policies
A 2020 report found that experts specializing in tobacco addiction recommended that those who wish to quit smoking take varenicline over all other treatment options