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Somatic mutation(s) of LKB1 , a tumor suppressor to upregulate AMPK-related catabolic and anabolic pathways, is viewed as an important cause of cancer development and poor prognosis in patients with NSCLC, hepatocarcinoma, and colorectal cancer [30, 37, 38]

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The Smoking Toolkit Study uses raking to weight the sample to match the population in England [34]

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