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10.1093/sexmed/qfae018 17 GiraseT.PatilJ.TatiyaA.PatilD.PatilM
(2020b) identified eEANs in contact with intestinal epithelial cells can detect microbes and their metabolites, specifically SCFAs, bile acids, and neuropeptides, via vagal afferents and subsequently sympathetically modulate gut activity via a CNS-directed circuit (Muller et al., 2020b)
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It was added to the Prohibited List in 2022 as a non-approved substance, reflecting its transition from an obscure research compound to a significant "substance of interest" in professional athletics
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