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Less Common but Serious Side Effects While rare, some individuals may experience more serious reactions, including: Severe dehydration: If nausea, vomiting, or diarrhea conditions persist, dehydration can become a risk

If the injection goes too deep (into muscle) or too shallow (intradermal), absorption rates change, and the effective dose differs from the intended dose

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Why TB Meningitis Has Resisted Better Treatment for Two Decades Tuberculosis primarily infects the lungs, but a small fraction of cases take a far more dangerous turn: the bacteria breach the blood-brain barrier, invade the central nervous system, and trigger a granulomatous inflammatory response that causes collateral damage to blood vessels, disrupts the blood-brain barrier, and kills neurons, as described in the StatPearls TBM chapter