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Smoking, primarily through the component nicotine, triggers an interaction with nicotinic acetylcholine receptors (nAChRs) on immune cells, particularly T cells and macrophages

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In this article, we provide an overview of the cannabis plant and its chemical components, the biology of the endocannabinoid system (ECS) and summarize current findings about the modulation of the pulmonary immune response from inhalation of cannabis products, including smoke and vapor

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