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Honest caveat: These mechanism findings do not prove the same pathways operate at the same magnitude in humans

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Real-time qPCR was performed using an Applied Biosystems QuantStudio 12 K Flex real time PCR system (Thermo Fisher Scientific, San Jose, CA, USA) with THUNDERBIRD SYBR qPCR Mix (Toyobo), 6 pmol of primers, and aliquots of cDNA

Exercise naturally activates many of the same pathways that berberine influences, including AMPK activation

It requires prompt medical attention and can range from mild, self-limiting episodes to severe, life-threatening complications