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T2DM is the most common endocrine disorder, characterised by insulin resistance and impaired insulin secretion, and it is one of the fastest growing non-communicable diseases in the world (Reference Shaw, Sicree and Zimmet9)

The liver clears it almost entirely through cytochrome P450 enzymes, with CYP3A4 responsible for roughly 90% of its oxidative metabolism

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Article 5 mins Captive Insurance: Uptick in Use Reflects Market Realities As more companies become comfortable using captives and understanding the value they add, captives are likely to become further embedded into corporate risk strategies, regardless of market conditions

Rwnolegle wskazuje si jego zwizek z przebudow tkankow, aktywnoci metaloproteinaz oraz rwnowag pomidzy syntez i degradacj elementw macierzy zewntrzkomrkowej