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While this review summarizes the current evidence from preclinical and clinical studies, most of the existing findings are based on animal models or short-term use human studies, which may not fully reflect the consequences of regular use in humans

It is crucial that people who use these products prioritize regular dental check-ups to screen for these potential issues and maintain good oral hygiene daily.

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Other Issues to Be Aware of Now, beyond the serious health complications like cardiovascular disease and cancer, there are other issues to be aware of