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The main costs to businesses we expect are losses in profits associated with: reduced sales of the products in scope to retailers, wholesalers and manufacturers packaging redesign costs costs of producing leaflets for products not already subject to the requirements time to familiarise themselves and comply with the regulations We took a conservative approach to estimating costs in the consultation stage impact assessment

Hu X, Ma Z, Wen L, Li S, Dong Z

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These agents also reduce eicosanoid-mediated inflammation by inhibiting the enzyme cyclooxygenase

Effects fade after 20-30 minutes