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EBioMedicine 70 , 103536 (2021)

If the commercial value of the new matter is meaningful only in combination with the original invention a specific dosing titration method for a particular formulation of a specific API claiming them separately in different patent families would produce claims too narrow to enforce without asserting both families

As a water-based treatment, the serum needs direct skin contact for optimal absorption

Ipamorelin, by contrast, has been the compound of choice when investigators need to stimulate a discrete GH pulse with high receptor selectivity and minimal interference from concurrent cortisol or ACTH axis activation

In research contexts, it is studied as a discrete pentadecapeptide with reproducible physicochemical properties, allowing its use in biochemical, cellular, and preclinical experimental systems