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A cigar thats smoked too quickly can become too hot, altering the flavors and making the smoke harsher

A woman leans back in quiet indulgence, a cigarette poised between her lips as smoke drifts upward

In support of a change in smoke composition, the yields of four aromatic amines and benzo[a]pyrene, NNK and CO decreased more than the tar yield with decreasing cigarette circumference, while formaldehyde yields increased

Another drawback of case control studies is that the exposure measure (cannabis use) has to be assessed retrospectively