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In summary, early studies suggest that vaping impacts the absorption of inhaled therapies by causing an increase in airway resistance and significant inflammation

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PLoS ONE 11 , e0163962 (2016)

Yes, you may feel initially stimulated as it floods your brain in a bath of short-term dopamine, serotonin and gamma-aminobutyric acid, or GABA, release, but the subsequent drop in neurotransmitter levels can depress your mood and make you more likely to experience negative intrusive thoughts, anger and anxiety