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As with other emerging tobacco products, the different levels of nicotine and the option to use flavors in oral pouches continue to be attractive features, with more than 85% of people who use these products selecting a flavored one

The buildup of these substances can lead to more serious dental issues, such as gum disease

A case of acute alveolitis with intra-alveolar fibrosis, infiltration of macrophages, eosinophils and neutrophils has been described by Itoh et al (42)

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Researchers don't know about all the side effects yet