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this phenomenon demonstrates that IR may be responsible for increased cardiovascular disease risk ( The administration of DPP-4 promotes IR (115, 116), and insulin sensitivity has been shown to be improved when DPP-4 was down-regulated (111, 117)

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doi: 10.1056/NEJMoa1612917 81 RuffCTBaronMImKODonoghueMLFiedorekFTSabatineMS

If it appears cloudy or has visible particles, it may indicate contamination, incomplete dissolution, or a problem with the peptide itself